Reappearance of limbal pigmentation post-simple limbal epithelial transplant
نویسندگان
چکیده
منابع مشابه
Assessment of surgical outcomes of limbal transplantation using simple limbal epithelial transplantation technique in patients with total unilateral limbal deficiency.
This study aimed to evaluate the effectiveness of the novel simple limbal epithelial transplantation (SLET) technique, which reduces the risk of iatrogenic limbal stem cell deficiency in the donor eye. Four patients with total unilateral limbal stem cell deficiency received a limbal graft, measuring 4 mm × 2 mm, from the contralateral healthy eye in a single surgical procedure. The graft was di...
متن کاملManagement of Unilateral Limbal Stem Cell Deficiency by Simple Limbal Epithelial Transplantation – Our Experience
Simple Limbal Epithelial Transplantation (SLET) has been proposed recently for care of total Limbal Stem Cell Deficiency (LSCD) secondary to alkali burn of cornea [1]. Reportedly it combines advantages of conjunctival limbal auto grafting [2] and cultivated limbal epithelial transplantation [3] by being a single-stage, affordable procedure utilizing minimal donor tissue. Besides, it is also rep...
متن کاملThe Limbal Epithelial Progenitors in the Limbal Niche Environment
Limbal epithelial progenitors are stem cells located in limbal palisades of vogt. In this review, we present the audience with recent evidence that limbal epithelial progenitors may be a powerful stem cell resource for the cure of human corneal stem cell deficiency. Further understanding of their mechanism may shed lights to the future successful application of stem cell therapy not only to the...
متن کاملLimbal epithelial crypt: a model for corneal epithelial maintenance and novel limbal regional variations.
OBJECTIVE To determine the distribution of cell membrane proteins and extracellular matrix proteins around the limbal epithelial crypt (LEC) compared with adjacent limbus and corneal epithelium. METHODS Serial histological sections of human corneoscleral limbus rims were stained with antibodies of interest by standard immunohistochemistry. RESULTS Superficial cells of the limbus were desmog...
متن کاملThe phenotype of limbal epithelial stem cells.
PURPOSE The purpose of this study was to identify phenotypic markers of human limbal stem cells in fetal and adult corneas. METHODS RNA from microscopically dissected superficial limbal and central fetal (18 weeks) corneas was amplified and used to generate P(32)-labeled, reverse-transcribed antisense RNA that was linearly amplified and hybridized to a focused stem cell cDNA microarray. Diffe...
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ژورنال
عنوان ژورنال: Indian Journal of Ophthalmology
سال: 2020
ISSN: 0301-4738
DOI: 10.4103/ijo.ijo_155_19